Gene Therapy for Heart Cells

Mount Sinai researchers led by Hina Chaudhry reported gene therapy for heart cells.
Cyclin A2 gene reactivation creates functional adult human heart cells.
Study published in npj Regenerative Medicine on November 3, 2025.
Viral vector delivered to donor hearts aged 21, 41, and 55.
Successful division observed in 41- and 55-year-old cells.
Researchers aim to seek FDA approval for heart disease treatment.
Gene delivery challenges include safety and controlled regeneration.
Dr. Hina Chaudhry called it a 20-year research achievement.
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